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1

Connective tissue growth factor modulates podocyte actin cytoskeleton and extracellular matrix synthesis and is induced in podocytes upon injury

Rudolf Fuchshofer, Sabrina Ullmann, Ludwig F. Zeilbeck, Matti Baumann, Benjamin Junglas, Ernst R. Tamm

Journal:

Histochemistry and Cell Biology

Year:

2011

Language:

english

File:

PDF, 1.62 MB

english, 2011

2

The role of TGF-β in the pathogenesis of primary open-angle glaucoma

Rudolf Fuchshofer, Ernst R. Tamm

Journal:

Cell and Tissue Research

Year:

2012

Language:

english

File:

PDF, 247 KB

english, 2012

3

Different collagen types define two types of idiopathic epiretinal membranes

Michaela Kritzenberger, Benjamin Junglas, Carsten Framme, Horst Helbig, Veit-Peter Gabel, Rudolf Fuchshofer, Ernst R Tamm, Jost Hillenkamp

Journal:

Year:

2011

Language:

english

File:

PDF, 1.29 MB

english, 2011

4

CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration

Braig, S, Wallner, S, Junglas, B, Fuchshofer, R, Bosserhoff, A-K

Journal:

British Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 456 KB

english, 2011

5

Elevated amounts of myocilin in the aqueous humor of transgenic mice cause significant changes in ocular gene expression

Walter Paper, Markus Kroeber, Sebastian Heersink, Dietrich A. Stephan, Rudolf Fuchshofer, Paul Russell, Ernst R. Tamm

Journal:

Experimental Eye Research

Year:

2008

Language:

english

File:

PDF, 740 KB

english, 2008

6

Connective Tissue Growth Factor Causes Glaucoma by Modifying the Actin Cytoskeleton of the Trabecular Meshwork

Benjamin Junglas, Sabrina Kuespert, Amin A. Seleem, Tobias Struller, Sabrina Ullmann, Michael Bösl, Anja Bosserhoff, Josef Köstler, Ralf Wagner, Ernst R. Tamm, Rudolf Fuchshofer

Journal:

The American Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 4.78 MB

english, 2012

7

Thrombospondin-1 in the trabecular meshwork: localization in normal and glaucomatous eyes, and induction by TGF-β1 and dexamethasone in vitro

Cassandra Flügel-Koch, Andreas Ohlmann, Rudolf Fuchshofer, Ulrich Welge-Lüssen, Ernst R. Tamm

Journal:

Experimental Eye Research

Year:

2004

Language:

english

File:

PDF, 717 KB

english, 2004

8

Hypoxia/reoxygenation and TGF-β increase αB-crystallin expression in human optic nerve head astrocytes

Alice L. Yu, Rudolf Fuchshofer, Marco Birke, Siegfried G. Priglinger, Kirsten H. Eibl, Anselm Kampik, Hans Bloemendal, Ulrich Welge-Lussen

Journal:

Experimental Eye Research

Year:

2007

Language:

english

File:

PDF, 1.11 MB

english, 2007

9

Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11

Antje Wurm, Elisabeth Sock, Rudolf Fuchshofer, Michael Wegner, Ernst R. Tamm

Journal:

Experimental Eye Research

Year:

2008

Language:

english

File:

PDF, 8.03 MB

english, 2008

10

Gene expression profiling of TGFβ2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-β2 signaling

Rudolf Fuchshofer, Dietrich A. Stephan, Paul Russell, Ernst R. Tamm

Journal:

Experimental Eye Research

Year:

2009

Language:

english

File:

PDF, 681 KB

english, 2009

11

Modulation of extracellular matrix turnover in the trabecular meshwork

Rudolf Fuchshofer, Ernst R. Tamm

Journal:

Experimental Eye Research

Year:

2009

Language:

english

File:

PDF, 176 KB

english, 2009

12

Hypoxia/reoxygenation induces CTGF and PAI-1 in cultured human retinal pigment epithelium cells

Rudolf Fuchshofer, Alice L. Yu, Hiang-Hwa Teng, Rupert Strauss, Anselm Kampik, Ulrich Welge-Lussen

Journal:

Experimental Eye Research

Year:

2009

Language:

english

File:

PDF, 801 KB

english, 2009

13

Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells

Benjamin Junglas, Alice H.L. Yu, Ulrich Welge-Lüssen, Ernst R. Tamm, Rudolf Fuchshofer

Journal:

Experimental Eye Research

Year:

2009

Language:

english

File:

PDF, 650 KB

english, 2009

14

The pathogenic role of transforming growth factor-β2 in glaucomatous damage to the optic nerve head

Rudolf Fuchshofer

Journal:

Experimental Eye Research

Year:

2011

Language:

english

File:

PDF, 284 KB

english, 2011

15

What Increases Outflow Resistance in Primary Open-angle Glaucoma?

Ernst R. Tamm, Rudolf Fuchshofer

Journal:

Survey of Ophthalmology

Year:

2007

Language:

english

File:

PDF, 86 KB

english, 2007

16

The effect of TGF-β2 on human trabecular meshwork extracellular proteolytic system

Rudolf Fuchshofer, Ulrich Welge-Lussen, Elke Lütjen-Drecoll

Journal:

Experimental Eye Research

Year:

2003

Language:

english

File:

PDF, 373 KB

english, 2003

17

Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype

Konstantin Dirscherl, Marcus Karlstetter, Stefanie Ebert, Dominik Kraus, Julia Hlawatsch, Yana Walczak, Christoph Moehle, Rudolf Fuchshofer, Thomas Langmann

Journal:

Journal of Neuroinflammation

Year:

2010

Language:

english

File:

PDF, 2.07 MB

english, 2010

18

Correction: Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype

Konstantin Dirscherl, Marcus Karlstetter, Stefanie Ebert, Dominik Kraus, Julia Hlawatsch, Yana Walczak, Christoph Moehle, Rudolf Fuchshofer, Thomas Langmann

Journal:

Journal of Neuroinflammation

Year:

2012

Language:

english

File:

PDF, 244 KB

english, 2012

19

Heterozygote Wdr36-deficient mice do not develop glaucoma

Gallenberger, Martin, Kroeber, Markus, März, Loreen, Koch, Marcus, Fuchshofer, Rudolf, Braunger, Barbara M., Iwata, Takeshi, Tamm, Ernst R.

Journal:

Experimental Eye Research

Year:

2014

Language:

english

File:

PDF, 1.78 MB

english, 2014

20

Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma

Overby, D. R., Zhou, E. H., Vargas-Pinto, R., Pedrigi, R. M., Fuchshofer, R., Braakman, S. T., Gupta, R., Perkumas, K. M., Sherwood, J. M., Vahabikashi, A., Dang, Q., Kim, J. H., Ethier, C. R., Stamer

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

21

The Prostaglandin F 2α Analog Fluprostenol Attenuates the Fibrotic Effects of Connective Tissue Growth Factor on Human Trabecular Meshwork Cells

Fuchshofer, Rudolf, Kuespert, Sabrina, Junglas, Benjamin, Tamm, Ernst R.

Journal:

Journal of Ocular Pharmacology and Therapeutics

Year:

2014

Language:

english

File:

PDF, 419 KB

english, 2014

22

Identification of Adult Stem Cells in Schwalbe's Line Region of the Primate Eye

Braunger, B. M., Ademoglu, B., Koschade, S. E., Fuchshofer, R., Gabelt, B. T., Kiland, J. A., Hennes-Beann, E. A., Brunner, K. G., Kaufman, P. L., Tamm, E. R.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2014

Language:

english

File:

PDF, 966 KB

english, 2014

23

Optineurin associates with the podocyte Golgi complex to maintain its structure

Sippl, Christiane, Zeilbeck, Ludwig F., Fuchshofer, Rudolf, Tamm, Ernst R.

Journal:

Cell and Tissue Research

Year:

2014

Language:

english

File:

PDF, 18.50 MB

english, 2014

24

Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application

Pollinger, K., Hennig, R., Ohlmann, A., Fuchshofer, R., Wenzel, R., Breunig, M., Tessmar, J., Tamm, E. R., Goepferich, A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2013

Language:

english

File:

PDF, 1.14 MB

english, 2013

25

Subtoxic Oxidative Stress Induces Senescence in Retinal Pigment Epithelial Cells via TGF-β Release

Yu, Alice L., Fuchshofer, Rudolf, Kook, Daniel, Kampik, Anselm, Bloemendal, Hans, Welge-Lu¨ssen, Ulrich

Journal:

Investigative Ophthalmology & Visual Science

Year:

2009

Language:

english

File:

PDF, 659 KB

english, 2009

26

The regulation of connective tissue growth factor expression influences the viability of human trabecular meshwork cells

Kuespert, Sabrina, Junglas, Benjamin, Braunger, Barbara M., Tamm, Ernst R., Fuchshofer, Rudolf

Journal:

Journal of Cellular and Molecular Medicine

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

27

Biochemical and Morphological Analysis of Basement Membrane Component Expression in Corneoscleral and Cribriform Human Trabecular Meshwork Cells

Fuchshofer, Rudolf, Welge-Lu¨ssen, Ulrich, Lu¨tjen-Drecoll, Elke, Birke, Marco

Journal:

Investigative Ophthalmology & Visual Science

Year:

2006

Language:

english

File:

PDF, 450 KB

english, 2006

28

The Novel Activated Microglia/Macrophage WAP Domain Protein, AMWAP, Acts as a Counter-Regulator of Proinflammatory Response

Karlstetter, M., Walczak, Y., Weigelt, K., Ebert, S., Van den Brulle, J., Schwer, H., Fuchshofer, R., Langmann, T.

Journal:

The Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 1.15 MB

english, 2010

29

Anatomical Study of Pelvic Nerves in Relation to Seminal Vesicles, Prostate and Urethral Sphincter: Immunohistochemical Staining, Computerized Planimetry and 3-Dimensional Reconstruction

Ganzer, Roman, Stolzenburg, Jens-Uwe, Neuhaus, Jochen, Weber, Florian, Fuchshofer, Rudolf, Burger, Maximilian, Bründl, Johannes

Journal:

The Journal of Urology

Year:

2015

Language:

english

File:

PDF, 7.04 MB

english, 2015

30

The aqueous humor outflow pathways in glaucoma: A unifying concept of disease mechanisms and causative treatment

Braunger, Barbara M., Fuchshofer, Rudolf, Tamm, Ernst R.

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2015

Language:

english

File:

PDF, 912 KB

english, 2015

31

Bone Morphogenetic Protein-7 Is an Antagonist of Transforming Growth Factor-β2 in Human Trabecular Meshwork Cells

Fuchshofer, Rudolf, Yu, Alice H. L., Welge-Lu¨ssen, Ulrich, Tamm, Ernst R.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2007

Language:

english

File:

PDF, 714 KB

english, 2007

32

Transforming Growth Factor-β2 Modulated Extracellular Matrix Component Expression in Cultured Human Optic Nerve Head Astrocytes

Fuchshofer, Rudolf, Birke, Marco, Welge-Lussen, Ulrich, Kook, Daniel, Lu¨tjen-Drecoll, Elke

Journal:

Investigative Ophthalmology & Visual Science

Year:

2005

Language:

english

File:

PDF, 577 KB

english, 2005

33

Increased expression of olfactomedin-1 and myocilin in podocytes during puromycin aminonucleoside nephrosis

Bohr, D. C., Koch, M., Kritzenberger, M., Fuchshofer, R., Tamm, E. R.

Journal:

Nephrology Dialysis Transplantation

Year:

2011

Language:

english

File:

PDF, 14.82 MB

english, 2011

34

Heterozygous modulation of TGF-β signaling does not influence Müller glia cell reactivity or proliferation following NMDA-induced damage

Martina Kugler,Anja Schlecht,Rudolf Fuchshofer…

Journal:

Histochemistry and Cell Biology

Year:

2015

Language:

english

File:

PDF, 1.69 MB

english, 2015

35

Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling

U. Friedrich, S. Datta, T. Schubert, K. Plössl, M. Schneider, F. Grassmann, R. Fuchshofer, K. Tiefenbach, G. Längst, B. H. F. Weber

Year:

2015

Language:

english

File:

PDF, 671 KB

english, 2015

36

The role of astrocytes in optic nerve head fibrosis in glaucoma

Schneider, Magdalena, Fuchshofer, Rudolf

Journal:

Experimental Eye Research

Year:

2016

Language:

english

File:

PDF, 319 KB

english, 2016

37

Cyclic RGD peptides target human trabecular meshwork cells while ameliorating connective tissue growth factor-induced fibrosis

Hennig, Robert, Kuespert, Sabrina, Haunberger, Alexandra, Goepferich, Achim, Fuchshofer, Rudolf

Journal:

Journal of Drug Targeting

Year:

2016

Language:

english

File:

PDF, 1.06 MB

english, 2016

38

Hypertensive retinopathy in a transgenic angiotensin-based model

Reichhart, N., Haase, N., Crespo-Garcia, S., Skosyrski, S., Herrspiegel, C., Kociok, N., Fuchshofer, R., Dillinger, A., Poglitsch, M., Muller, D. N., Joussen, A. M., Luft, F. C., Dechend, R., Strauss,

Journal:

Clinical Science

Year:

2016

Language:

english

File:

PDF, 2.30 MB

english, 2016

39

SMAD7 deficiency stimulates Müller progenitor cell proliferation during the development of the mammalian retina

Kugler, Martina, Schlecht, Anja, Fuchshofer, Rudolf, Schmitt, Sabrina I., Kleiter, Ingo, Aigner, Ludwig, Tamm, Ernst R., Braunger, Barbara M.

Journal:

Histochemistry and Cell Biology

Year:

2017

Language:

english

File:

PDF, 5.71 MB

english, 2017

40

Norrin protects optic nerve axons from degeneration in a mouse model of glaucoma

Leopold, Stephanie A., Zeilbeck, Ludwig F., Weber, Gregor, Seitz, Roswitha, Bösl, Michael R., Jägle, Herbert, Fuchshofer, Rudolf, Tamm, Ernst R., Ohlmann, Andreas

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 5.77 MB

english, 2017

41

Oxidative Stress and TGF-β2 Increase Heat Shock Protein 27 Expression in Human Optic Nerve Head Astrocytes

Yu, Alice L., Fuchshofer, Rudolf, Birke, Marco, Kampik, Anselm, Bloemendal, Hans, Welge-Lu¨ssen, Ulrich

Journal:

Investigative Ophthalmology & Visual Science

Year:

2008

Language:

english

File:

PDF, 385 KB

english, 2008

42

Reactivation of Optic Nerve Head Astrocytes by TGF-β2 and H 2 O 2 Is Accompanied by Increased Hsp32 and Hsp47 Expression

Yu, Alice L., Moriniere, Jerome, Birke, Marco, Neumann, Carolin, Fuchshofer, Rudolf, Kampik, Anselm, Bloemendal, Hans, Welge-Lussen, Ulrich

Journal:

Investigative Ophthalmology & Visual Science

Year:

2009

Language:

english

File:

PDF, 606 KB

english, 2009

43

Cross-Inhibition of Norrin and TGF-β Signaling Modulates Development of Retinal and Choroidal Vasculature

Seitz, Roswitha, Weber, Gregor, Albrecht, Sebastian, Fuchshofer, Rudolf, Tamm, Ernst R., Ohlmann, Andreas

Journal:

Investigative Opthalmology & Visual Science

Year:

2018

Language:

english

File:

PDF, 1.46 MB

english, 2018

44

Encyclopedia of the Eye || Regulation of Extracellular Matrix Turnover in the Aqueous Humor Outflow Pathways*

Year:

2010

Language:

english

File:

PDF, 1.41 MB

english, 2010

45

Intracameral Delivery of Layer-by-Layer Coated siRNA Nanoparticles for Glaucoma Therapy

Dillinger, Andrea E., Guter, Michaela, Froemel, Franziska, Weber, Gregor R., Perkumas, Kristin, Stamer, W. Daniel, Ohlmann, Andreas, Fuchshofer, Rudolf, Breunig, Miriam

Journal:

Year:

2018

Language:

english

File:

PDF, 3.49 MB

english, 2018

46

Rezidivierende Schluckbeschwerden bei einem jungen Mann

Fuchshofer,, Külling,, Rüttimann,, Steiner,

Journal:

Year:

2009

File:

PDF, 212 KB

2009

47

Effects of Oxidative Stress in Trabecular Meshwork Cells Are Reduced by Prostaglandin Analogues

Yu, Alice L., Fuchshofer, Rudolf, Kampik, Anselm, Welge-Lu¨ssen, Ulrich

Journal:

Investigative Ophthalmology & Visual Science

Year:

2008

Language:

english

File:

PDF, 475 KB

english, 2008

48

Loss of retinal ganglion cells in a new genetic mouse model for primary open‐angle glaucoma

Reinehr, Sabrina, Koch, Dennis, Weiss, Maximilian, Froemel, Franziska, Voss, Christina, Dick, H. Burkhard, Fuchshofer, Rudolf, Joachim, Stephanie C.

Journal:

Journal of Cellular and Molecular Medicine

Year:

2019

Language:

english

File:

PDF, 1.34 MB

english, 2019

49

Loss of retinal ganglion cells in a new genetic mouse model for primary open‐angle glaucoma

Reinehr, Sabrina, Koch, Dennis, Weiss, Maximilian, Froemel, Franziska, Voss, Christina, Dick, H. Burkhard, Fuchshofer, Rudolf, Joachim, Stephanie C.

Journal:

Journal of Cellular and Molecular Medicine

Year:

2019

File:

PDF, 1.34 MB

2019

50

Norrin Protects Retinal Ganglion Cells from Excitotoxic Damage via the Induction of Leukemia Inhibitory Factor

Kassumeh,, Leopold,, Fuchshofer,, Thomas,, Priglinger,, Tamm,, Ohlmann,

Journal:

Year:

2020

Language:

english

File:

PDF, 3.04 MB

english, 2020